Cholibrium is a 60-capsule, 30-day-supply dietary supplement sold by Simple Promise around a 10-mushroom heart-health and antioxidant positioning. The merchant currently lists one-time package pricing from $39 to $59 per bottle depending on quantity and advertises a 365-day money-back guarantee. The key limitation is evidence: ingredient research is not the same as clinical evidence for the finished Cholibrium formula, and current dyslipidemia guidance does not recommend dietary supplements for lipid lowering.
What is Cholibrium?
Cholibrium is marketed by Simple Promise as a “Healthy Heart and Antioxidant Formula.” The current product page says the formula contains ten mushrooms and is sold as 60 capsules, with directions to take two capsules with an 8-ounce glass of water and a meal, or as directed by a healthcare provider.
The merchant names Reishi, Lion’s Mane, Cordyceps, Shiitake, Maitake, Turkey Tail, Chaga, Royal Agaricus, White Button and Black Fungus. Those ingredients make Cholibrium meaningfully different from cholesterol-oriented products based on plant sterols, soluble fiber, red yeast rice or bergamot.
What does the evidence actually establish?
The safe distinction is between product evidence and ingredient evidence. A study involving a mushroom or a mushroom-derived compound does not automatically demonstrate that Cholibrium itself produces a clinically meaningful change in LDL cholesterol, blood pressure, or cardiovascular outcomes.
Price and value
At the time of this update, the merchant lists one-time prices of $59 for one bottle, $49 per bottle for three bottles, and $39 per bottle for six bottles. Prices, subscriptions, shipping and terms can change, so verify the final checkout before purchasing.
| Package | Current merchant listing | Approx. supply |
|---|---|---|
| 1 bottle | $59 | 30 days |
| 3 bottles | $49/bottle | 90 days |
| 6 bottles | $39/bottle | 180 days |
Safety considerations
“Natural” does not mean risk-free. Mushroom products can be unsuitable for some people, and supplements can interact with medications or health conditions. This site does not attempt to determine whether Cholibrium is appropriate for you. Ask your healthcare professional, particularly if you use prescription medication, have a diagnosed cardiovascular condition, are pregnant, or are preparing for surgery.
What stands out—and what remains uncertain?
Useful facts
- Named 10-mushroom formula
- 60 capsules / 30-day supply
- Current merchant page displays a 365-day guarantee
- Vegan, Paleo and Keto-friendly according to the merchant
Limitations
- Ingredient evidence is not finished-product evidence
- No supplement should replace clinician-directed cholesterol management
- Individual outcomes cannot be predicted from testimonials
- Current price and policies should be checked at checkout
Who should consider alternatives first?
If your primary goal is to lower diagnosed high cholesterol, start with professional medical guidance. If you are specifically shopping for a supplement category with clearer evidence on cholesterol levels, review our guides to plant sterols and psyllium before deciding.
Sources & verification
- Simple Promise — Cholibrium product page (product details, directions, package pricing and merchant claims).
- NCCIH — High Cholesterol and Dietary Supplements (independent evidence context).
- 2026 ACC/AHA Dyslipidemia Guideline (clinical management context).
- FTC Health Products Compliance Guidance (health-claim substantiation and disclosure principles).